Blood coagulation is a process through which several proteins combine together to form a fibrin stopper, whose function is to arrest the bleeding. The deficiency of one of the proteins involved in this process can cause minor or serious hemorrhagic manifestation. The gravity of the pathology depends on the factor's role in the coagulation fall, the entity of the factor deficiency, which can be partial or total, and on the functionality of the factor itself.
In Western countries, the most frequent inherited disorders are Hemophilia A and B, with a frequency of 1:10.000 and 1:50.000 respectively. At present, in Italy, there are specific Centers that provide accurate diagnosis, therapy and treatment to the patients who suffer from hemophilia A and B. Yet, the knowledge of the "rare bleeding" disorders (Rare Bleeding Disorders: RBDs), which affect 1 person out of 500.000-2.000.000 in the world, is still less-than-perfect.

Our centre focuses on disorders like hemophilia and rare bleeding disorders